Recommended doses of fexofenadine are: For adults with seasonal allergic rhinitis (hay fever): 120 mg taken once a day web. For kids aged 6-12 years with seasonal allergic rhinitis (hay fever): 30 mg taken twice 1 day, in the morning and evening. For adults with chronic urticaria: 180 mg taken once a day.
Fexofenadine is not available OTC. Patients currently prescribed fexofenadine 120mg for hay fever should be encouraged to purchase an alternative antihistamine OTC. Fexofenadine should be reserved for patients that are intolerant of or even unresponsive to cetirizine or even loratadine.
The first possible anti-inflammatory effect for fexofenadine was introduced by Abdelaziz who suggested that suggest that fexofenadine may reduce nasal inflammation by modulating the release of proinflammatory mediators and adhesion molecules from human nasal epithelial cell go to website.
One trial reported that fexofenadine was superior to loratadine with regards to wheal and flare suppression (allergic skin reaction), with a faster onset of effect and a more effective suppression of the flare at each time point in the study (Kaliner et al).
Several studies have found cetirizine (Zyrtec) to be better than fexofenadine (Allegra) at relieving symptoms of allergic rhinitis and urticaria, and it seems to have a lengthier duration of action.